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New Medicine

        <h2>Guide to Live Events in Sioux City: Concerts, Sports and Shows Near You</h2>
<p>Sioux City, Iowa is a vibrant destination for live entertainment, featuring concerts, theater, major sporting events and music festivals. Whether you're cheering on your favorite team or catching a chart-topping artist live, Vivid Seats makes it simple to secure great seats.</p>
        
        <h2>Things to Do in Sioux City This Week</h2> 
        
<p>This week fans can cheer on the <a href="https://www.vividseats.com/sioux-city-explorers-tickets--sports-minor-league-baseball/performer/19867">Sioux City Explorers</a> at <a href="https://www.vividseats.com/sioux-city-explorers-tickets-mercy-field-at-lewis-and-clark-park-8-17-2025--sports-minor-league-baseball/production/5307301">Mercy Field at Lewis and Clark Park</a> for a thrilling minor league baseball matchup. For a change of pace the legendary <a href="https://www.vividseats.com/the-spinners-tickets/performer/5431">The Spinners</a> roll into <a href="https://www.vividseats.com/the-spinners-tickets-sloan-winnavegas-casino-8-16-2025--concerts-rb/production/5775837">WinnaVegas Casino</a> with their signature R and B classics.</p>        
        <h2>Things to Do in Sioux City Next Week</h2> 
        
<p>Sioux City’s Orpheum Theatre springs to life next week when <a href="https://www.vividseats.com/gabby-barrett-tickets/performer/124770">Gabby Barrett</a> kicks off a night of country on August 22 and <a href="https://www.vividseats.com/clint-black-tickets/performer/184">Clint Black</a> follows the next evening. Meanwhile the Hard Rock Hotel and Casino Sioux City hosts comedian <a href="https://www.vividseats.com/josh-blue-tickets--theater-comedy/performer/11000">Josh Blue</a> before turning into a dance floor with <a href="https://www.vividseats.com/the-spazmatics-tickets/performer/145424">The Spazmatics</a>, and on the 24th baseball fans can cheer on the <a href="https://www.vividseats.com/sioux-city-explorers-tickets--sports-minor-league-baseball/performer/19867">Sioux City Explorers</a> at Mercy Field at Lewis and Clark Park.</p>

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Concert, Comedy, Sports & Theater Tickets in Sioux City, IA

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Hard Rock Hotel and Casino Sioux City

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New Medicine at Hard Rock Hotel and Casino Sioux City

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New Medicine Hard Rock Hotel and Casino Sioux City in Sioux City, IA Thu, Oct 16 at 7:00pm